Tickborne encephalitis (TBE) and Lyme borreliosis are well-established infections in the Nordic region and represent a substantial part of routine clinical practice within infectious diseases, neurology, and clinical microbiology.

In recent years, increasing attention has been directed toward long-term clinical outcomes, particularly following neuroinvasive disease. Several Nordic studies indicate that a proportion of patients experience persistent symptoms after TBE, including neurological, cognitive, and functional impairments. In Lyme borreliosis, diagnostic complexity – especially in suspected neuroborreliosis and in patients with ongoing or recurrent symptoms after treatment – continues to pose challenges in daily clinical practice.

Prevention strategies, including vaccination against TBE, are implemented to varying degrees across the Nordic countries. Endemic regions with long-standing vaccination programs offer valuable real-world insights into disease epidemiology, severity, and outcomes over time.

This symposium aims to provide an evidence-based overview of long-term sequelae, diagnostic challenges, and prevention of tick-borne diseases, facilitating knowledge exchange across Nordic countries and clinical specialties.